Yes. When the pipe's internal roughness, internal diameter and length are known, together with the type and number of fittings on the pipe, plus the change in elevation between the start and end of the pipe, then for a specified flow rate, the pressure drop in the pipe can be calculated.

The type of flow that occurs (laminar or turbulent), the associated Reynolds number, and the friction factor used in the pressure drop calculation are also displayed alongside the pipe pressure loss result.